Epic Journey: Did Moses' Exodus Really Happen?













In the Bible, he is called Moses. In the Koran, he is the prophet Musa.


Religious scholars have long questioned whether of the story of a prophet leading God's chosen people in a great exodus out of Egypt and the freedom it brought them afterwards was real, but the similarities between a pharaoh's ancient hymn and a psalm of David might hold the link to his existence.


Tune in to Part 2 of Christiane Amanpour's ABC News special, "Back to the Beginning," which explores the history of the Bible from Genesis to Jesus, on Friday, Dec. 28 at 9 p.m. ET on ABC.


Christian scripture says Moses was content to grow old with his family in the vast deserted wilderness of Midian, and 40 years passed until the Bible says God spoke to him through the Burning Bush and told him to lead his people, the Israelites, out of Egypt. According to tradition, that miraculous bush can still be seen today enclosed within the ancient walls of St. Catherine's Monastery, located not far from Moses' hometown.


But there was another figure in the ancient world who gave up everything to answer the call from what he believed was the one and only true God.


Archaeologists discovered the remains of the ancient city of Amarna in the 1800s. Egyptologist Rawya Ismail, who has been studying the ruins for years, believes, as other archaeologists do, that Pharaoh Akhenaten built the city as a tribute to Aten, the sun.






G.Sioen/De Agostini/Getty Images











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She said it was a bold and unusual step for the pharaoh to leave the luxurious trappings of palace life in Luxor for the inhospitable landscape of Amarna, but it might have been his only choice as the priests from the existing religious establishment gained power.


"The very powerful Amun-Ra priests that he couldn't stand against gained control of the whole country," Ismail said. "The idea was to find a place that had never been used by any other gods -- to be virgin is what he called it -- so he chose this place."


All over the walls inside the city's beautiful tombs are examples of Akhanaten's radical message of monotheism. There is the Hymn to the Aten, which translates, in part, to: "The earth comes into being by your hand, as you made it. When you dawn, they live. When you set, they die. You yourself are lifetime, one lives by you."


PHOTOS: Christiane Amanpour's Journey 'Back to the Beginning'


Some attribute the writing of the hymn to Akhanaten himself, but it bears a striking resemblance to a passage that can be found in the Hebrew Bible: Psalm 104.


"If you compare the hymns from A to Z, you'll find mirror images to it in many of the holy books," Ismail said. "And if you compare certain parts of it, you'll find it almost exactly -- a typical translation for some of the [psalms] of David."


Psalm 104, written a few hundred years later, references a Lord that ruled over Israel and a passage compares him to the sun.


"You hide your face, they are troubled," part of it reads. "You take away your breath, they die, And return to dust. You send forth your breath, they are created, And you renew the face of the earth."


Like the psalm, the Hymn to Aten extols the virtues of the one true God.


"A lot of people think that [the Hymn to Aten] was the source of the [psalms] of David," Ismail said. "Putting Egypt on the trade route, a lot of people traveled from Egypt and came back to Egypt, it wasn't like a country living in isolation."


Ismail believes it is possible that the message from the heretic pharaoh has some connection to the story of Moses and the Exodus, as outlined in the Hebrew Bible.




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India gang rape victim dies in Singapore hospital


SINGAPORE/NEW DELHI (Reuters) - An Indian woman whose gang rape in New Delhi triggered violent protests died of her injuries on Saturday in a Singapore hospital, bringing a security lockdown in Delhi and recognition from India's prime minister that social change is needed.


The Indian capital braced for a new wave of protests, closing metro stations and banning vehicles from the city centre district where young activists had converged to demand improved women's rights. The news came in the early hours of the morning in India and there were no signs of protests as morning broke.


The 23-year-old medical student, severely beaten, raped and thrown out of a moving bus in New Delhi two weeks ago, had been flown to Singapore in a critical condition by the Indian government on Thursday for specialist treatment.


"We are very sad to report that the patient passed away peacefully at 4:45 a.m. on Dec 29, 2012 (2045 GMT Friday). Her family and officials from the High Commission (embassy) of India were by her side," Mount Elizabeth Hospital Chief Executive Officer Kelvin Loh said in a statement.


Indian Prime Minister Manmohan Singh said in a statement he was deeply saddened by the death and described the emotions associated with her case as "perfectly understandable reactions from a young India and an India that genuinely desires change.


"It would be a true homage to her memory if we are able to channelize these emotions and energies into a constructive course of action."


Delhi's Chief Minister, Sheila Dikshit, expressed revulsion.


"It is a shameful moment for me not just as a chief minister but also as a citizen of this country," she said.


The woman, who has not been identified, and a male friend were returning home from the cinema by bus on the evening of December 16 when, media reports say, six men on the bus beat them with metal rods and repeatedly raped the woman. The reports say a rod was used in the rape, causing internal injuries. Both were thrown from the bus. The male friend survived the attack.


Singh's government has been battling criticism that it was tone-deaf to the outcry that followed the attack and was heavy handed in its response to the protests in the Indian capital.


Most rapes and other sex crimes in India go unreported and offenders are rarely punished, women's rights activists say. But the brutality of the December 16 assault sparked public outrage and calls for better policing and harsher punishment for rapists.


VEHICLES BARRED FROM DELHI CITY CENTRE


T.C.A. Raghavan, the Indian High Commissioner to Singapore, told reporters hours after the woman's death that a chartered aircraft would fly her body back to India on Saturday, along with members of her family. The woman's body had earlier been loaded into a van at the hospital and driven away.


In New Delhi, the Joint Commissioner of Traffic Police, Satyendra Garg, told NDTV news channel that residents and commuters were advised to avoid the city centre.


The case has received blanket coverage on cable television news channels. Some Indian media have called the woman "Amanat", an Urdu word meaning "treasure".


Talking to reporters earlier on Saturday, Raghavan declined to comment on Indian media reports accusing the government of sending her to Singapore to minimize the possible backlash in the event of her death.


Some Indian medical experts had questioned the decision to airlift the woman to Singapore, calling it a risky maneuver given the seriousness of her injuries. They had said she was already receiving the best possible care in India.


But Dr B.D. Athani, medical superintendent of the New Delhi hospital where she had initially been treated, told Indian television the intention was to give the victim the best chance of surviving in what he described as "an extreme case".


"Her condition was very critical from day one. We had managed what best we could do at our end ... she had to be shifted to a centre with much better facilities."


On Friday, the Singapore hospital had said the woman's condition had taken a turn for the worse. It said she had suffered "significant brain injury". She had already undergone three abdominal operations before arriving in Singapore.


The suspects in the rape - five men aged between 20 and 40, and a juvenile - were arrested within hours of the attack and are in custody. Media reports say they are likely to be formally charged with murder next week.


Commentators and sociologists say the rape tapped into a deep well of frustration many Indians feel over what they see as weak governance and poor leadership on social and economic issues.


Many protesters have complained that Singh's government has done little to curb the abuse of women in the country of 1.2 billion. A global poll by the Thomson Reuters Foundation in June found that India was the worst place to be a woman because of high rates of infanticide, child marriage and slavery.


New Delhi has the highest number of sex crimes among India's major cities, with a rape reported on average every 18 hours, according to police figures. Government data show the number of reported rape cases in the country rose by nearly 17 percent between 2007 and 2011.


(Additional reporting by Ross Colvin and Devidutta Tripathy in New Delhi; Saeed Azhar, Edgar Su and Sanjeev Miglani in Singapore; Editing by Michael Roddy, Ron Popeski and Mark Bendeich)



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Delhi police urge calm after gang-rape victim dies






NEW DELHI: New Delhi's top police officer and chief minister on Saturday urged people to mourn the death of a gang-rape victim in a peaceful manner as large parts of the city-centre were sealed off.

Police Commissioner Neeraj Kumar asked people to maintain calm across the city, according to a statement from his office which also announced that the area around the India Gate monument and 10 metro stations would be closed to the public.

New Delhi chief minister Sheila Dikshit also appealed for calm and pledged "solid steps will be taken very soon" to protect women in India's capital.

"Please maintain peace and at the same time we must make sure that every action is taken to make women secure in our city," she told reporters.

The calls for calm came after an Indian woman who was gang-raped on a New Delhi bus died a Singapore hospital early Saturday after suffering severe organ failure.

People across India have started coming out to mourn the death of the 23-year-old student, whose death has already sparked mass protests.

Police said they would allow people to hold peaceful demonstrations only in some areas and hundreds of policemen have been deployed to prevent any violence on the streets.

Indian Prime Minister Manmohan Singh also said he was deeply saddened by the death and the protests that were sparked by the case were "understandable".

- AFP/ck



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New iOS app shows NY subway arrival times



Now arriving...



(Credit:
New York MTA)



New York City's Metropolitan Transportation Authority finally joined the smartphone era today by releasing an iOS app showing train arrival times for seven subway lines.



Available for the iPhone, the
iPod Touch, and the
iPad, MTA Subway Time will display train arrival times for 156 stations on the 1, 2, 3, 4, 5, 6 lines and the S shuttle line. Though officially in a test version for the time being, the app will use the same arrival times shown on station countdown clocks and on the MTA's Web site.



"The ability to get subway arrival time at street level is here," said MTA Chairman and CEO Joseph J. Lhota in a statement. "The days of rushing to a subway station only to find yourself waiting motionless in a state of uncertainty are coming to an end."



According to the statement, the app can handle up to 5,000 incoming requests per second. The information comes from a feed that can be accessed by developers for other mobile operating systems.



Though the MTA has existing apps for bus arrivals and the drive times on its bridges and tunnels, this is the first time that the country's busiest transit agency has developed an app for subway service.



Via AllThings D


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Classes delayed for Sandy Hook Elementary kids

NEWTOWN, Conn. The children at the Sandy Hook Elementary school won't be returning to classes for another week, but officials from the town, school district and local agencies are doing their best in the meantime to keep them occupied following a massacre at their school two weeks ago.

The students have not attended school since a gunman killed 20 of their schoolmates and six adults on Dec. 14. They are slated to return to a different school next Thursday.

In the meantime, they've been treated to field trips, toy giveaways and some organized play time.

"A couple of the teachers have done pizza parties," said Janet Robinson, Newtown's school superintendent. "Another met her kids at the library so they could have a little reading time together. The most important thing has been connecting the students back to their teacher and their classmates."




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Newtown schools superintendent: We have to move forward






39 Photos


Victims of Conn. school shooting






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Newtown police get a break on Christmas



The Newtown Youth Academy, a nonprofit sports center, opened its doors to all kids in town at no cost shortly after the shooting. But from 9 a.m. to 2 p.m. last week, the building's turf field, basketball and tennis courts, and giant inflatable obstacle course were reserved just for Sandy Hook Elementary students.

There have been arts and crafts for the smaller kids, as well as face-paintings. Some celebrities, including two members of the Harlem Globetrotters and former University of Connecticut basketball star Tina Charles, also have stopped by to play with the children.

UConn's men's basketball team and its coaches made a trip to the academy Thursday and played games with the kids, posed for photos and signed autographs. "It was great for us to be able to see some smiles on their faces and to spend some time with them," Coach Kevin Ollie said.

On Thursday afternoon, school buses were loading up at the Youth Academy for a trip to Stamford and a larger complex, Chelsea Piers, which also has ice rinks and an indoor swimming pool, said academy owner Peter D'Amico. Sports celebrities, such as Brooklyn Nets forward Kris Humphries, planned to meet them there.

"The idea was to get them away from the house, the television and all the coverage of this tragedy and get them to a place where kids can just be kids," said D'Amico, a longtime youth coach in town.

University of Connecticut psychologist Julian Ford, who spent time counseling in Newtown in the first days after the shooting, said it's important for the grieving process to include an outlet that lets children know that while things will never be the same, it's OK to enjoy life.

"They are all going to be thinking about what happened," he said. "That, unfortunately, is inescapable. But this gives them a chance to say, `Life is carrying on.' Nothing will be the same, but it's also continuing in ways that it should be."

Some students and their parents on Thursday toured the Chalk Hill school in Monroe, a former middle school being reopened next week for the Sandy Hook students. An open house is planned for Wednesday.

"Getting back into the school is like getting back on the horse," Robinson said. "Some of the scariness is gone once they cross that threshold. They are just so happy to see their teachers."

State police said they plan to keep their contact with the children to a minimum as they continue investigating the shooting.

"We certainly don't want to traumatize them any more than they've already been traumatized," said Lt. J. Paul Vance, the department's spokesman. "If (an interview is) not necessary it won't be done. Our investigators will make all those determinations."

In the meantime, Ford has encouraged parents to keep the kids involved in a normal holiday routine and deal with the tragedy as it comes up, rather than making it a focal point of their lives.

David Connors, who has 8-year-old triplets who attend Sandy Hook, said he and his wife have made play dates with their friends, brought the kids to see family for the holidays and participated in the class get-togethers and recreation events.

"That's been, I think, helpful at least in the short term just to kind of keep them doing things, keep them seeing their friends and being nearby and talking to family," Connors said.

Todd Wood of Newtown has five children, the youngest age 4 and the oldest in college. His children's piano teacher lost a child in the shooting, and the family knows other victims as well.

He said he's found that each child has reacted differently to the tragedy. He said he is not making the shooting the center of his family's life but is not pretending it didn't happen, either.

"We did Christmas, we had our lights here, we've tried to make things as normal as possible," he said. "But we also went down to see the memorials. I don't want to shield them from it. I want to let them grieve in their own way."

Ford said that is healthy. He said children will remember their friends as they go about doing normal kid things.

Chris Wolcott, the sport's academy's operations manager, said the best part of having the kids at the center is that the tragedy is pushed aside, at least for a little while.

"A couple times someone would drop a weight (in the facility's health center) and you would hear a bang and there would be a kid who would freeze for a second," he said. "But that would last a split-second. Most of the time, everyone just had a great time."

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Gen. 'Stormin' Norman Schwarzkopf Dead at 78













H. Norman Schwarzkopf, the retired general credited with leading U.S.-allied forces to a victory in the first Gulf War, died today at age 78.


The man who Defense Secretary Leon Panetta today called "one of the great military giants of the 20th century" died in Tampa, Fla., where he lived in retirement, the Associated Press reported.


"The men and women of the Department of Defense join me in mourning the loss of General Norman Schwarzkopf, whose 35 years of service in uniform left an indelible imprint on the United States military and on the country," Panetta said in a statement. "My thoughts and prayers are with the Schwarzkopf family in this time of sadness and grief."


Schwarzkopf, called "Stormin' Norman" because of his reportedly explosive temper, led America to two military victories: a small one in Grenada in the 1980s and a big one as de facto commander of allied forces in the Gulf War in 1991.


"'Stormin' Norman' led the coalition forces to victory, ejecting the Iraqi Army from Kuwait and restoring the rightful government," read a statement by former Secretary of State Colin Powell, who was chairman of the Joint Chiefs of Staff during the Gulf War. "His leadership not only inspired his troops, but also inspired the nation."


WATCH: Gen. Norman Schwarzkopf to Saddam Hussein: 'Get Outta Town'


Schwarzkopf's success during that fight, also known as Operation Desert Storm, came under President George H.W. Bush, who through his office today mourned "the loss of a true American patriot and one of the great military leaders of his generation."








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"Gen. Norm Schwarzkopf, to me, epitomized the 'duty, service, country' creed that has defended our freedom and seen this great nation through our most trying international crises," Bush said. "More than that, he was a good and decent man -- and a dear friend."


Bush's office released the statement though the former president, himself, was ill, hospitalized in Texas with a stubborn fever and on a liquids-only diet.


The current White House occupant, President Obama, also memorialized Schwarzkopf, declaring him "an American original" who "stood tall for the country and Army he loved."


The future four-star general was born Aug. 24, 1934, in Trenton, N.J.


Schwarzkopf's father, who shared his name, directed the investigation of the Lindbergh baby kidnapping as head of the New Jersey State Police, later becoming a brigadier general in the U.S. Army.


Schwarzkopf was raised as an army brat in Iran, Switzerland, Germany and Italy, following in his father's footsteps to West Point, earning an engineering degree and being commissioned as a second lieutenant in 1956.


WATCH: Gen. Schwarzkopf's '5 Minutes of Unimportant Questions'


He earned three Silver Stars for bravery during two tours in Vietnam, gaining a reputation as an opinionated, plain-spoken commander with a sharp temper who would risk his own life for his soldiers.


"He had volunteered to go to Vietnam early just so he could get there before the war ended," said former Army Col. William McKinney, who knew Schwarzkopf from their days at West Point, according to ABC News Radio.


In 1983, as a newly-minted general, Schwarzkopf once again led troops into battle in President Reagan's invasion of Granada, a tiny Caribbean island where the White House saw American influence threatened by a Cuban-backed coup.


But he gained most of his fame in Iraq, where he used his 6-foot-3, 240-pound frame and fearsome temper to drive his forces to victory.


"He was known as a soldier's general," said retired Maj. Gen. Donald Shepperd, as he explained the "Stormin' Norman" nickname to ABC News Radio. "In other words, he really liked the troops and was soft on the troops. But boy, on his general officers, his officers, his NCO's, he was very, very tough and he had a real quick temper."


PHOTOS: In Memoriam: People We Lost in 2012


Gruff and direct, Schwarzkopf said during the Gulf War that his goal was to win the war as quickly as possible and with a focused objective: getting Iraq out of Kuwait.






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CAR appeals for French help against rebels, Paris balks


BANGUI (Reuters) - The president of the Central African Republic appealed on Thursday for France and the United States to help push back rebels threatening his government and the capital, but Paris said its troops were only ready to protect French nationals.


The exchanges came as regional African leaders tried to broker a ceasefire deal and as rebels said they had temporarily halted their advance on Bangui, the capital, to allow talks to take place.


Insurgents on motorbikes and in pickup trucks have driven to within 75 km (47 miles) of Bangui after weeks of fighting, threatening to end President Francois Bozize's nearly 10-year-stint in charge of the turbulent, resource-rich country.


French nuclear energy group Areva mines the Bakouma uranium deposit in the CAR's south - France's biggest commercial interest in its former colony.


The rebel advance has highlighted the instability of a country that has remained poor since independence from Paris in 1960 despite rich deposits of uranium, gold and diamonds. Average income is barely over $2 a day.


Bozize on Thursday appealed for French and U.S. military support to stop the SELEKA rebel coalition, which has promised to overthrow him unless he implements a previous peace deal in full.


He told a crowd of anti-rebel protesters in the riverside capital that he had asked Paris and Washington to help move the rebels away from the capital to clear the way for peace talks which regional leaders say could be held soon in Libreville, Gabon.


"We are asking our cousins the French and the United States, which are major powers, to help us push back the rebels to their initial positions in a way that will permit talks in Libreville to resolve this crisis," Bozize said.


France has 250 soldiers in its landlocked former colony as part of a peacekeeping mission and Paris in the past has ousted or propped up governments - including by using air strikes to defend Bozize against rebels in 2006.


But French President Francois Hollande poured cold water on the latest request for help.


"If we have a presence, it's not to protect a regime, it's to protect our nationals and our interests and in no way to intervene in the internal business of a country, in this case the Central African Republic," Hollande said on the sidelines of a visit to a wholesale food market outside Paris.


"Those days are over," he said.


Some 1,200 French nationals live in the CAR, mostly in the capital, according to the French Foreign Ministry, where they typically work for mining firms or aid groups.


CEASEFIRE TALKS


The U.N. Security Council issued a statement saying its members "condemn the continued attacks on several towns perpetrated by the 'SELEKA' coalition of armed groups which gravely undermine the Libreville Comprehensive Peace Agreement and threaten the civilian population."


U.S. State Department spokesman Patrick Ventrell said the U.S. embassy had temporarily suspended operations and the U.S. ambassador and other embassy personnel had left the country.


Officials from around central Africa are due to meet in Bangui later on Thursday to open initial talks with the government and rebels.


A rebel spokesman said fighters had temporarily halted their advance to allow dialogue.


"We will not enter Bangui," Colonel Djouma Narkoyo, the rebel spokesman, told Reuters by telephone.


Previous rebel promises to stop advancing have been broken, and a diplomatic source said rebels had taken up positions around Bangui on Thursday, effectively surrounding it.


The atmosphere remained tense in the city the day after anti-rebel protests broke out, and residents were stocking up on food and water.


Government soldiers deployed at strategic sites and French troops reinforced security at the French embassy after protesters threw rocks at the building on Wednesday.


In Paris, the French Foreign Ministry said protecting foreigners and embassies was the responsibility of the CAR authorities.


"This message will once again be stressed to the CAR's charge d'affaires in Paris, who has been summoned this afternoon," a ministry spokesman said.


He also said France condemned the rebels for pursuing hostilities and urged all sides to commit to talks.


Bozize came to power in a 2003 rebellion that overthrew President Ange-Felix Patasse.


However, France is increasingly reluctant to directly intervene in conflicts in its former colonies. Since coming to power in May, Hollande has promised to end its shadowy relations with former colonies and put ties on a healthier footing.


A military source and an aid worker said the rebels had got as far as Damara, 75 km (47 miles) from Bangui, by late afternoon on Wednesday, having skirted Sibut, where some 150 Chadian soldiers had earlier been deployed to try and block a push south by a rebel coalition.


With a government that holds little sway outside the capital, some parts of the country have long endured the consequences of conflicts in troubled neighbors Chad, Sudan and the Democratic Republic of Congo spilling over.


The Central African Republic is one of a number of nations in the region where U.S. Special Forces are helping local forces try to track down the Lords Resistance Army, a rebel group responsible for killing thousands of civilians across four African nations.


(Additional reporting by Leigh Thomas and Louis Charbonneau; Writing by Richard Valdmanis; Editing by Andrew Osborn and Paul Simao)



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Clinton, still recovering, back at desk Monday






WASHINGTON: Outgoing US Secretary of State Hillary Clinton, who fell ill in early December and has not been seen in public since, will be back at her desk on Monday, her closest aide said.

"She's recuperating at home," and will take up her official duties again "next week", Philippe Reines wrote in brief email to AFP when asked about the health of Washington's most travelled top diplomat.

Clinton, 65, has been off work sick since her return from her last trip on December 7, although her staff says she has been working from home.

Her lengthy absence from public life has sparked claims from some of her fiercer critics that she is trying to avoid testifying in a congressional investigation into a deadly attack on a US consulate in Libya.

The State Department said Clinton had contracted a bad stomach virus during her five-day stay in Europe. She had to cancel a planned trip to North Africa and Abu Dhabi due to the illness.

A week later, Clinton's doctors said she had become severely dehydrated due to the effects of the stomach bug and had fainted, suffering a concussion.

They recommended she rest at home and avoid, through mid-January, the high-intensity travel she had been accustomed to taking as secretary of state.

Clinton has flown almost a million miles since taking office four years ago, visited 112 countries and spent some 400 days in a plane.

Her health kept her from testifying on December 20 to US lawmakers about the attack on the US consulate in Benghazi, Libya, on September 11.

The assault, in which the US ambassador and three other US officials were killed, sparked a political firestorm in the US, and Republicans criticized Clinton's absence last week, calling on her to testify in January.

Clinton, who is due to step down from her post in early 2013, also stayed away from the White House last Friday when President Barack Obama nominated her replacement, veteran senator John Kerry.

She issued a long statement paying tribute to her successor, and the State Department has regularly assured the public that Clinton continues to work from home, but that has not prevented questions over her three weeks of absence.

- AFP/al



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Autonomy founder fires back at HP after news of DOJ inquiry



Autonomy founder Mike Lynch



(Credit:
HP)


Autonomy founder and former CEO Mike Lynch is firing back at Hewlett-Packard after the release of HP's annual report with the U.S. Securities and Exchange Commission today. The report states that the federal government opened an inquiry into HP's acquisition of Autonomy in November and hints that Autonomy's accounting is partially to blame.

"It is extremely disappointing that HP has again failed to provide a detailed calculation of its $5 billion write-down of Autonomy, or publish any explanation of the serious allegations it has made against the former management team, in its annual report filing today," Lynch said in an e-mailed statement. "Furthermore, it is now less clear how much of the $5 billion write-down is in fact being attributed to the alleged accounting issues, and how much to other changes in business performance and earnings projections."

HP acquired the enterprise software company in August 2011 for $11.1 billion, or 11 times its annual earnings. Since the purchase, controversy, lawsuits, and an $8.8 billion charge against HP's earnings have ensued.

HP and Lynch have traded arguments in the press over who deserves the blame for Autonomy's subpar performance. In its fourth-quarter earnings release last month, HP said it had discovered "extensive evidence" of fraudulent accounting and failed disclosures on Autonomy's part leading up to the sale. Consequently, Lynch set up a Web site that denies HP's charges and says HP mishandled the company after acquiring it.

"We also do not understand why HP is raising these issues now given that Autonomy reported into the HP Finance team from the day the acquisition completed in October 2011, there was an extensive due diligence process and Autonomy was audited as a public company for many years," Lynch said today. "We also note the statement in HP's annual report that it received confirmation from the U.S. Department of Justice on 21 November 2012 (the day after HP's first public statement), that the Department had opened an investigation. We can confirm that we have as yet had no contact from any regulatory authority. We will co-operate with any investigation and look forward to the opportunity to explain our position."


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Study: Cancer drug substitute linked to higher rate of relapse

(CBS News) Abby Alonzo was 10 when she was diagnosed in 2009 with Hodgkin's lymphoma, a cancer of the immune system. With proper treatment, 90 percent of patients survive.

"It wasn't as hard for me as I think it as it was on my mom and my brother and my dad," Abby says.

Abby began a seven-drug regimen. But in 2010, doctors told Abby's mother, Katie, there was a nationwide shortage of one of the medicines -- mechlorethamine.

"I started to get a little hysterical, 'Why is it not available?'" says Katie.

In 2010, 23 cancer drugs had shortages. Reasons include manufacturing problems and low profit margins for the drugs, which became mostly generic, and therefore less expensive, than brand-name.

"There is really nothing you can do," Katie says. "You do what your doctor tells you to do, you take what medications your doctor tells you to take, and you pray that it works. And if one of those medications isn't available, you just take, you know, the next-best thing."

Doctors thought the next-best thing for patients like Abby was a drug called cyclophosphamide.

Life-saving cancer drugs for children stuck in federal legislative limbo

But a new study in the New England Journal of Medicine showed 88 percent treated with the original drug were cancer-free after two years -- compared to only 75 percent of those receiving the replacement drug.

"This is the first study to clearly show that when we substitute one drug for what we think is just an equally good drug, that's not always going to be the case. So it's demonstrating a negative impact on patients," says Dr. Richard Gilbertson, the director of cancer care at St. Jude Children's Research Hospital.

Abby was one of the patients who relapsed. She then needed a bone marrow transplant, radiation and more chemotherapy. Right now, she shows no signs of cancer.

"What if I relapsed again? Or what if something else happens? You know, it is just really scary, that part," Abby says.

The original drug in the study is finally available again after almost three years. But there are still 13 drugs used in cancer therapy, and a total of 100 on the FDA shortage list.

Congress passed legislation last July giving the FDA more authority to deal with cancer drug shortages. That new law has made a big difference, and the key provision is the requirement that drug manufacturers let the FDA know when there's an impending shortage.

Since that law was passed, there has been a doubling of those notifications, so the FDA can increase imports from abroad and tell other manufacturers in the United States to step up production.

Another provision in that law is that the FDA set up a task force looking at other possible solutions to the drug shortage crisis, and they're required to submit that report to Congress by this coming July.

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